Coyote Cartography

I've spent the past 2 years out of work, Unable to get anything from a contract to a cashier's job. My own brother (manager of a clothing store) told me that he wouldn't hire me because there's plenty of people that have worked in retail that he could hire already, and they get so many applications for every opening he can't bother to read them all anyway. All I've been looking for is work in what I "used" to do, windows system engineering/administration/architecture, but there's the part of me that's tired of it after about 7 years of doing it, and was just about ready to give up anyway when I lost my job. I have a degree in, of all things, Biology, which is mostly useless for employment, it being 11 years old now. I'm just in a complete state of not knowing what to do about anything at times, regretting not going back to school for some retraining two years ago, but then the issue was "what to train in" because I could never really answer the question, "Well, what do I want to do"...